There is a lot of research going on with regard to pemetrexed.

Use of pemetrexed in breast cancer

In vitro synergistic cytotoxicity of gemcitabine and pemetrexed and pharmacogenetic evaluation of response to gemcitabine in bladder cancer patients.

Phase II study of pemetrexed plus carboplatin in malignant pleural mesothelioma.

Dramatic tumour response to pemetrexed single-agent in an elderly patient with malignant peritoneal mesothelioma: a case report